Mechanistic study of structural effects on nucleophilic substitution reactions at sulfonyl centers

Nucleophilic substitution processes at the sulphur atom of arenesulfonyl compounds have been the subject of numerous discussions among experts for many years. This is due to the ambiguity of the solvolysis mechanism, which is often treated as a bimolecular with different symmetry at the transition state, catalytic assistance of the solvent, a possible rearrangement during the nucleophilic attack, etc. In the last years, the problem has become more complicated by the study of these reactions i...