Acción de la simvastatina en la contracción de músculo liso de anillo traqueal inducida por estím...

The tracheal smooth muscle contraction is associated with a significant entry of Ca2+ into the cell and depletion of intracellular stores. Simvastatin, relaxes the basilar artery by decreasing intracellular Ca2 +. The objective was to study the effect of simvastatin on smooth muscle contraction of isolated rat trachea before and after being stimulated with acetylcholine and cold water. 8 rats were anesthetized with sodium tiobarbital 60 mg/kg ip, to remove the windpipe and cut the rings, were...